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Coming soon from EpitomeRx: Nº 29 copper peptide cream. Learn more
EpitomeRx skincare

N 29

GHK-Cu Multipeptide Cream

A daily face cream built around 0.5% high-purity copper peptide, with two supporting peptides and zinc hydrolyzed hyaluronate, to visibly soften the look of lines and wrinkles and leave skin looking smoother and more hydrated.

1.06 oz (30 g) airless pump · Fragrance & dye free

Nº 29 airless pump bottle on a travertine plinth in window light
Why 29

Named for copper, element 29.

Copper sits at number 29 on the periodic table, and it sits at the center of this cream. Nº 29 carries 0.5% high-purity copper tripeptide-1 (GHK-Cu), the copper peptide valued in skincare for helping skin look smoother, healthier and more resilient.

Nº 29 is made with the pure powder, in a base designed to keep peptides stable from the first pump to the last.

0.5%GHK-Cu
4key ingredients
0fragrance or dyes
29CuCOPPER63.55
Front and back of the Nº 29 bottle on a sapphire background
The formula

Four key ingredients, working as one.

Each ingredient has a job. Together they target the look of lines, texture and dryness in a single step.

01

Copper Tripeptide-1

GHK-Cu · 0.5%

The copper peptide at the heart of Nº 29. Helps skin look healthier, smoother and more resilient.

02

Centella Asiatica Leaf Extract

Centella-derived peptide complex

Drawn from centella, a plant long used in skincare, to condition skin and support its natural surface.

03

Acetyl Hexapeptide-8

Expression-line peptide

A peptide chosen to soften the look of expression lines, for a smoother, more relaxed-looking finish.

04

Zinc Hydrolyzed Hyaluronate

Hydration partner

A zinc-bound form of hyaluronic acid that draws in moisture and helps keep skin hydrated, supple and comfortable.

The peptides

Peptides, simply put.

Peptides are short chains of amino acids, the same building blocks that make up the proteins in skin, like collagen and elastin. Compared with collagen, peptides are tiny. Compared with what skin lets in, they are large, so the base around them matters.

Nº 29 is a multipeptide cream: three peptide ingredients, each with its own job, in one formula.

Copper Tripeptide-1 (GHK-Cu)

Three amino acids (glycine, histidine and lysine) paired with copper. First identified in the 1970s, GHK-Cu has become one of the most studied peptides in skincare, valued for helping skin look smoother, healthier and more resilient over time. It is the lead ingredient in Nº 29 at 0.5%. It is also where the cream gets its soft blue color.

Acetyl Hexapeptide-8

A chain of six amino acids created for the look of expression lines, the ones that form with everyday movement, like those across the forehead. One of the most widely used peptides in modern skincare, it helps skin look smoother and more relaxed.

Centella Asiatica Peptide Complex

A peptide-rich complex drawn from centella asiatica, a plant used in skincare traditions for centuries. It conditions skin and supports its natural surface, working alongside the copper peptide.

The results

What eight weeks looked like.

In an 8-week pilot study, 14 women ages 40 to 60 used the same cream as Nº 29 every morning and evening after cleansing. 3D facial imaging measured their lines at the start, at 4 weeks and at 8 weeks. The biggest changes were in moderate and deeper lines, not fine lines.

13 of 14women showed a measurable reduction in the look of wrinkles
72%showed visible improvement by week 4
0adverse events reported, and every participant completed the study

Small single-group pilot study without a control group, conducted by the supplier of the base formula. Nº 29 uses that formula unchanged. Individual results vary.

Naturally pale blue

The soft blue tint comes from the copper peptide itself. No dyes and no added fragrance, just a light, silky cream.

Sealed in an airless pump

Peptides are sensitive to air and light. The airless bottle keeps both out and dispenses a clean, measured amount every time.

A dollop of pale blue Nº 29 cream on travertine
How to use

Morning and evening.

  1. Cleanse and gently pat skin dry.
  2. Smooth one to two pumps over face and neck, avoiding the eye area.
  3. In the morning, follow with sunscreen.

Good to know. Use vitamin C, AHAs or BHAs, azelaic acid, benzoyl peroxide, or brightening products with hydroquinone or kojic acid at the opposite time of day. They can make copper peptides less active.

Caution: For external use only. Avoid the eye area. Discontinue use if irritation develops.

Formulated without

  • Fragrance
  • Dyes
  • Lanolin
  • Gluten
  • Nuts
  • Animal-derived ingredients

Store at room temperature, away from direct sunlight. Use within 12 months of opening.

Questions

Good questions.

Questions? Call our pharmacist at 626.631.6150.

Do I need a prescription?

No. Nº 29 is a cosmetic skincare product, so no prescription is needed.

Why is the cream blue?

Copper peptide is naturally blue. The color comes from the GHK-Cu, not from dyes.

Can I use Nº 29 with my other skincare?

Yes. Use it as your moisturizing step, morning and evening. Don't apply it at the same time as vitamin C (ascorbic acid), azelaic acid, AHAs or BHAs such as glycolic, lactic or salicylic acid, benzoyl peroxide, or brightening products with hydroquinone or kojic acid. They can make the copper peptide less active and change the cream's smell. Use those at the opposite time of day. In the morning, finish with your favorite sunscreen.

When will I notice a difference?

In the 8-week study, 72% of participants showed visible improvement by week 4. For a fair read, use Nº 29 twice daily for at least eight weeks.

Who makes Nº 29?

Nº 29 is made in the USA and distributed by EpitomeRx, a compounding pharmacy in Arcadia, California. Questions? Call our pharmacist at 626.631.6150.

What's in it?

Water, Cyclopentasiloxane, Ethylhexyl Stearate, Coconut Alkanes, Cetearyl Alcohol, Caprylic/Capric Triglyceride, Dimethicone, Dimethyl Isosorbide, Glycerin, Centella Asiatica Leaf Extract, Copper Tripeptide-1, Acetyl Hexapeptide-8, Zinc Hydrolyzed Hyaluronate, Coco-Caprylate/Caprate, Polyacrylate-13, Ceteth-10 Phosphate, Dicetyl Phosphate, Polyisobutene, Polysorbate 20, Ethylhexylglycerin, Phenoxyethanol, Sodium Hydroxide.

29CuCOPPER63.55

Nº 29 GHK-Cu Multipeptide Cream

1.06 oz (30 g) airless pump · Fragrance & dye free

Nº 29 is a cosmetic product intended to improve the appearance of skin. It is not intended to diagnose, treat, cure or prevent any disease. Distributed by EpitomeRx, Inc. Made in USA.